Would you like to be more informed about the range of potential treatment options for your health problem? Would you consider a clinical trial? If you are considering participating in a clinical trial, please check the resources for understanding clinical trials.
A clinical trial is a research study that evaluates the effectiveness and safety of new medications or medical devices to help with your health problem. Clinical trials may be the way for you to receive promising new therapies that are not available otherwise.
To view studies taking place at the University of Pittsburgh, please visit Pitt+Me to search by research study area.
Please check the extensive U.S. National Institutes of Health Clinical Trials database. This service is provided by the United States National Institutes of Health. The site provides free access to information on clinical studies for a wide range of diseases and conditions. Clinical trials from all over the world are included in this database.
The UPMC Vision Institute has numerous open trials. Please check our list below.
UPMC Vision Institute Currently Enrolling Clinical Trials
If you are interested in any of our currently enrolling clinical trials, please call our triage number: 412-642-7888
- Cornea Studies
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Condition Study Nickname Title of Study Study Coordinator Status Persistent Corneal Epithelial Defect CHASE A Study to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants with Persistent Corneal Epithelial Defect (PCED) Alec Bertoni
bertoniar@upmc.eduRecruiting Keratoconus CXL A Multicenter, Randomized, Double-Masked, Sham-Controlled, Parallel-Group Phase 3 Study to Evaluate the Efficacy and Safety of Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age with Keratoconus (APRICITY-A) Alec Bertoni
bertoniar@upmc.eduRecruiting Neurotrophic Keratopathy SEER-2 A Phase 3, Multi-Center, Randomized, Parallel, Double Masked, Placebo-Controlled Clinical Study to Assess the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of Neurotrophic Keratopathy (SEER-2) Chad Indermill
indermillc@upmc.eduRecruiting Hyperopia TENEO A Study to Investigate the Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia with or Without Astigmatism Dipanwita Samanta
samantad@upmc.eduRecruiting - Glaucoma Studies
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Condition Study Nickname Title of Study Study Coordinator Status Glaucoma,
Ocular HypertensionCOAST Clarifying the Optimal Application of SLT Therapy Trial Sashan Morris
morriss10@upmc.eduNo longer recruiting - Pediatric Studies
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Condition Study Nickname Title of Study Study Coordinator Status Myopia Ocumension OT_101_001: A phase III, randomized, double masked, placebo controlled, parallel group, multicenter study of the safety and efficacy of OT 101 (Atropine Sulfate 0.01%) in treating the progression of myopia in pediatric subjects Shrutika Jadhav jadhavsm3@upmc.edu Active, not recruiting Myopia Essilor FIN-3101: A multicenter, randomized, controlled, prospective, 2-armed, parallel-group, double-masked, 3-year clinical trial to evaluate the myopia control effectiveness of the FIN C2 lens compared to single vision lens Shrutika Jadhav jadhavsm3@upmc.edu Active, not recruiting Retinopathy of Prematurity ROP4 PEDIG-ROP4: Bevacizumab Treatment for Type I Retinopathy of Prematurity (ROP) Shrutika Jadhav jadhavsm3@upmc.edu Recruiting Amblyopia ATS22 AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old Shrutika Jadhav jadhavsm3@upmc.edu Not yet recruiting Retinal Dystrophies Uni-Rare Universal Rare Gene Study: A Registry and Natural History Study of Retina Dystrophies Associated with Rare Disease-Causing Genetic Variants Shrutika Jadhav jadhavsm3@upmc.edu Not yet recruiting - Retina Studies
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Condition Study Nickname Title of Study Study Coordinator Status Uveitis ACELYRIN A Phase 2b Pivotal Study to Evaluate the Efficacy and Safety of Izokibep in Subjects with Non-infectious, Intermediate-, Posterior- or Pan-uveitis Rhonda Dahlstrom
dahlstromrj@upmc.eduNo longer recruiting AMD, nAMD, wAMD, CNV ASCENT A Randomized, Partially Masked, Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD Sashan Morris
morriss10@upmc.eduRecruiting Choroideremia, Retinitis Pigmentosa ENVISION Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-015 in Patients with Retinitis Pigmentosa (ENVISION) Rhonda Dahlstrom
dahlstromrj@upmc.eduSashan Morris
morriss10@upmc.eduNot yet recruiting Geographic Atrophy OCUGEN A Phase 1/2 Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration Sashan Morris
morriss10@upmc.eduNo longer recruiting Inherited Retinal Diseases NOPROD Global Patient Registry of Inherited Retinal Diseases Natalie Anthony
anthonynl2@upmc.eduRecruiting Retinitis Pigmentosa PRODYGY A Phase I/II Study to Assess the Safety and Tolerability of a Single Subretinal Administration of SPVN06 Gene Therapy in Subjects with Rod-Cone Dystrophy (RCD) Due to a Mutation in the RHO, PDE6A, or PDE6B Gene Natalie Anthony
anthonynl2@upmc.eduRecruiting Inherited Retinal Degeneration, Retinitis Pigmentosa UNI-RARE Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated with Rare Disease-Causing Genetic Variants Chad Indermill
indermillc@upmc.eduRecruiting X-Linked Retinitis Pigmentosa VISTA A Randomized, Controlled, Masked, Multi-center Study Evaluating the Efficacy, Safety, and Tolerability of Two Doses of AGTC-501 Compared to an Untreated Control Group in Male Participants with X-linked Retinitis Pigmentosa Dipanwita Samanta
samantad@upmc.eduRecruiting