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Bryan W. Jones, PhD

  • Professor of Ophthalmology

Dr. Bryan Jones is a retinal neuroscientist whose scientific work involves understanding the topology of neural circuitry and what the evolution of neural circuitry can teach us about information processing. His work is funded through the study of disease and understanding how neural structure, organization, and circuitry changes in neurodegenerative disease.

Understanding how we perceive the world through neural circuits involved in vision is compelling enough to Dr. Jones, but understanding how neural circuits are altered in diseases like retinitis pigmentosa, glaucoma, age-related macular degeneration, and Alzheimer’s drives his work.

Division

    Education & Training

  • Postdoctoral Fellow Moran Eye Center (Ophthalmology)
  • Postdoctoral Fellow Huntsman Cancer Institute (Cell Biology)
  • PhD in Neurophysiology University of Utah 2003
  • BS in Biology and Chemistry University of Utah 1996
Awards
2024 Research to Prevent Blindness Stein Innovation Award
2020 Research to Prevent Blindness International Scholars Award
2015 Wellcome Trust Winner, Wellcome Image Awards
2013 Federation of American Societies for Experimental Biology (FASEB)
2012 Winner Scientific Visualization Challenge, National Science Foundation (NSF)
2010 State of Utah Innovation Award
2006 Research to Prevent Blindness Career Development Award
2004 Young Investigator Award, RD
2004 The Association for Research in Vision and Ophthalmology Travel Award
Representative Publications

Retinal remodeling triggered by photoreceptor degenerations. BW Jones, CB Watt, JM Frederick, W Baehr, CK Chen, EM Levine, et al. Journal of comparative neurology 464 (1), 1-16.

Retinal remodeling in human retinitis pigmentosa. BW Jones, RL Pfeiffer, WD Ferrell, CB Watt, M Marmor, RE Marc. Experimental eye research 150, 149-165.

Persistent remodeling and neurodegeneration in late-stage retinal degeneration. RL Pfeiffer, RE Marc, BW Jones. Progress in Retinal and Eye Research.

A pathoconnectome of early neurodegeneration: Network changes in retinal degeneration. RL Pfeiffer, JR Anderson, J Dahal, JC Garcia, JH Yang, CL Sigulinsky, BW Jones, et al. Experimental eye research 199, 108196.

Retinal connectomics: a review. CL Sigulinsky, RL Pfeiffer, BW Jones. Annual Review of Vision Science 10 (1), 263-291.

Full list of publications

Research Interests

Neural circuitry
Connectomics
Pathoconnectomics
Neurodegeneration
Retina

Research Grants

Retinal Circuitry
Principal Investigator(s): Bryan W. Jones
National Institutes of Health / National Eye Institute

Research Gift
Principal Investigator(s): Bryan W. Jones
An unrestricted grant from Gabe Newell

Stein Innovation Award
Principal Investigator(s): Bryan W. Jones
Research to Prevent Blindness

Cell-based therapies for retinal degeneration
Co-Principal Investigator(s): Valeria Canto Soler, Bryan W. Jones
National Institutes of Health / National Eye Institute

Mesoscale correlative light-electron microscopy (CLEM)
Co-Principal Investigator(s): Gianluca Lazzi, Michael Bienkowski, Bryan W. Jones

NeuroNex: Enabling Identification and Impact of Synaptic Weight in Functional Networks
Principal Investigator(s): Kristen Harris, Bryan W. Jones is a sub-awardee
National Science Foundation

Proline metabolism in retinal health
Principal Investigator(s): Jianhai Du, Bryan W. Jones is a sub-awardee
National Institutes of Health / National Eye Institute