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Gabrielle R. Bonhomme, MD

  • Division Chief, Neuro-Ophthalmology Service
  • Assistant Professor of Ophthalmology
  • Fellowship Director, Neuro-Ophthalmology

Gabrielle R. Bonhomme, MD, serves as Division Chief of Neuro-Ophthalmology and is the sole full-time Ophthalmology and Neuro-Ophthalmology fellowship-trained adult Neuro-Ophthalmologist for the UPMC system, with a broadening referral base of 300 square miles. The UPMC Vision Institute division of Neuro-Ophthalmology is the singular referral center for patients with Neuro-ophthalmologic disorders in the region, and receives referrals from a growing number of neurologists, ophthalmologists, and neurosurgeons in western PA, Maryland, West Virginia, and New York, as well as many international patients referred via the UPMC Global Care program. Her clinical areas of interest include intracranial hypertension, neoplasia of the sella and skull base, and patients with neuro-oncologic disorders.

    Education & Training

  • University of Pennsylvania Health System, Fellowship
  • Scheie Eye Institute, Residency
  • University of Pennsylvania Health System, MD
Representative Publications

Skull base chordomas presenting with abducens nerve deficits: clinical characteristics and predictive factors for deficit improvement or resolution.
Muthiah N, Gersey ZC, Le L, Abdallah H, Abou-Al-Shaar H, Stefko ST, Bonhomme GR, Kocasarac C, Wang EW, Snyderman CH, Gardner PA, Zenonos GA. J Neurosurg. 2025 Jan 17;142(6):1682-1690. doi: 10.3171/2024.8.JNS232831. Print 2025 Jun 1.

Implementation of high-definition fiber tractography for preoperative evaluation and surgical planning of brainstem cavernous malformation: long-term outcomes. Fernandes Cabral DT, Zenonos GA, Barrios-Martinez J, Bonhomme GR, Yeh FC, Fernandez-Miranda JC, Friedlander RM. J Neurosurg. 2024 Nov 29;142(4):968-976. doi: 10.3171/2024.7.JNS24454. Print 2025 Apr 1.

Anterolateral keyhole transorbital routes to the skull base: a comparative anatomical study. Karampouga M, Terrarosa AK, Patel B, Affolter K, Wang EW, Choby GW, Fu R, Bonhomme GR, Stefko ST, McDowell MM, Snyderman CH, Gardner PA, Zenonos GANeurosurg Focus. 2024 Apr;56(4):E3. doi: 10.3171/2024.2.FOCUS23877.

Retinal neovascularization in Susac's syndrome: A rare imaging finding. Adeghate JO, Bonhomme GR, Indermill C, Taylor SL, Rocha M, Moghadam-Kia S, Errera MH. Oman J Ophthalmol. 2023 Oct 18;16(3):570-572. doi: 10.4103/ojo.ojo_330_22. eCollection 2023 Sep-Dec.

Hidden in the Eyes-Recurrence of Systemic Hemopathies Reportedly "In Remission": Six Cases and Review of Literature. Denier M, Tick S, Dubois R, Dulery R, Eller AW, Suarez F, Burroni B, Maurage CA, Bories C, Konopacki J, Puech M, Bouscary D, Cantalloube A, Héron E, Marçais A, Habas C, Theillac V, Keilani C, Bonhomme GR, Gallagher DS, Boumendil J, Abarah W, Sedira N, Bertin S, Choquet S, Sahel JA, Merabet L, Brignole-Baudouin F, Putterman M, Errera MH. Medicina (Kaunas). 2022 Mar 21;58(3):456. doi: 10.3390/medicina58030456.

Full list of publications

Ongoing studies

  • RECOVER Gensight LHON study - first on-site meeting achieved. Recruiting Dr. Martel retinal faculty for IV injections, recruiting Dr. Gallagher as well, working with our IRB liaison, Carla Aubourg.
  • VIRES group has resulted in several publications on neurosurgical approaches using HDFT.
  • 2018 – present: Creating a longitudinal database of subjects with PCA strokes to study using OCT, fMRI, and DTI techniques in collaboration with CMU and Dr. Bradford Mahon of the University of Rochester.

Book chapters

  • Giant cell arteritis-associated ocular vascular diseases, Marie-Helene Errera, Thomas M. Pearce, and Gabrielle Bonhomme. Retinal and Choroidal Vascular Diseases of the Eye 1st Edition, Jay Chhablani, MD Editor, Elsevier Books, March 2024
Research Interests

Dr. Bonhomme's research interests include improving the evaluation of the efficacy of venous sinus stenting in subjects with vision loss due to IIH (OPEN-UP study), the diagnosis of para-neoplastic syndromes affecting the vision of subjects with lung cancer, creating an algorithm to predict post-operative results in subjects with vision-threatening anterior visual pathway tumors, creating a multi-disciplinary longitudinal database of subjects with PCA strokes to study using OCT, fMRI, and DTI techniques, and investigating the use of HDFT MRI post-processing technique in pre-operative planning. 

Research Grants
  • 2012 - present:  CAR study/ PATHs Award - University of Pittsburgh Medical School PATHS Pilot Program Grant to be used to fund this pilot study on improving the diagnosis of para-neoplastic syndromes affecting the vision of subjects with lung cancer.